Mike Yastrzemski, Jung Hoo Lee, Wilmer Flores and Patrick Bailey each drove in two runs as the San Francisco Giants posted an 11-4 victory over the host Philadelphia Phillies on Wednesday.

Tyler Fitzgerald added three hits and scored twice for San Francisco, which has won two of the first three contests in this four-game series. The Giants, who had 13 hits on Wednesday, have captured five of their last seven games overall.

Bryce Harper’s two-run homer was a highlight for Philadelphia, which has lost five of its last seven. Phillies right-hander Aaron Nola was uncharacteristically wild for the second straight start as he remained winless on the young season at 0-4.

Lee opened the scoring with a first-inning RBI single against Nola and then came around to score on a bases-loaded walk to Flores. Bailey followed with a two-run single to make it 4-0.

Philadelphia responded with two runs in the bottom half of the frame, as San Francisco left-hander Robbie Ray walked four of the first seven hitters, including two free passes that forced in a run.

Harper tied it at 4-4 in the fourth with a two-run homer to right. However, the Giants responded with a run in the fifth as Lee doubled, advanced on a single and scored on center fielder Johan Rojas’ wild throw back to the infield.

Nola came back out for the sixth and allowed three straight one-out baserunners, including a pair of walks. Jose Ruiz came on in relief but walked Willy Adames to force in a run. Lee’s sacrifice fly made it 7-4.

The Giants blew open the game with four more runs against Joe Ross in the seventh, capped by Yastrzemski’s two-run double.

Ray was charged with four runs, six hits and five walks in four innings. Lou Trivino (1-1) worked two scoreless innings before relievers Camilo Doval and Spencer Bivens combined to slam the door.

Nola allowed seven runs (six earned), nine hits and four walks along with eight strikeouts in 5 1/3 innings as his ERA rose to 6.65 on the season.